Ok here it goes Jackie Kennedy's (JFK's wife) knew of FKS's afffairs with other women ironically enough !"Marilyn"! Monroe, but still kept he composure in the public eye, hence : There,s something cold and blank behind her smile.

she lived in a perfect world she grew up wealthy, and she was the wife of the fucking president of the united states hence :You were from a perfect world A world that threw me away today Today to run away"

it's kind of sad but all her life she was all ways in hell with her dads abusive relationships with women, all of her husbands were womanizers and cheated on her, her only way to cope with the pain and depression was her drug of choice, books, literature, art and culture, she used these things to fill a void in her life, but even all of the "drugs" she couldnt like to herself the problem was still there, around her and in her head hence: A pill to make you numb, A pill to make you dumb, A pill to make you anybody else, But all the drugs in this world, Won't save her from herself

the assasination of JFK had to be a mind fuck to her and a dagger to the heart because no matter how much of an ass he was to her she still loved this dude, of course she cried, depression set in she wanted to die, tears leaking from her eyes, crying like a kid who lost its doll (polaroid), hence:
Her mouth was an empty cut, And she was waiting to fall,Just bleeding like a polaroid that Lost all her doll

this song is in my opinion about her but more about the feeling of hopelessness, depression and sorrow, and emptiness, pain, plain and simple wanting to die that every person in this world at one time or another feels, he merely uses her as analigie, that's why he used to shooting of JFK in his video.

oh yea the El Día de los Muertos (day of the dead) parade going on kind of plays into him wanting to be dead he sees himself on the cross, in pictures and so forth , I dunno that's a hard one maybe that's just an element of the video who knows